
Dr Angelo Jayamanne
Neurologist & Neurophysiologist
About Dr Angelo Jayamanne
Dr Angelo Jayamanne is a skilled neurologist with a strong academic and clinical background. He obtained his medical degree from the University of Notre Dame (Fremantle) and is accredited in Neurology by the Royal Australasian College of Physicians (FRACP).
Alongside his clinical training, Dr Jayamanne completed a PhD in peripheral neuropathy and neuropathic pain, with his research published in peer-reviewed medical journals. His academic work contributes to advancing the understanding of nerve disorders and chronic neuropathic pain.
Dr Jayamanne further expanded his expertise through a Neurophysiology Fellowship at Prince of Wales Hospital, where he undertook specialised training in nerve conduction studies, electromyography and electroencephalography. This training underpins his advanced diagnostic capabilities for neuromuscular and neurological conditions.
He is committed to delivering high-quality, evidence-based care to patients with neurological concerns and has professional interests spanning neuromuscular disease, neurophysiology and general neurology.
Clinical Interests
Dr Jayamanne provides expert assessment and management across general and neuromuscular neurology, such as:
- General neurology.
- Neuromuscular disorders.
- Headaches.
- Peripheral neuropathy.
- Neuropathic pain.
He also offers specialist neurophysiological diagnostic testing and therapeutic intervention, including:
- Nerve conduction studies.
- Repetitive nerve stimulation.
- Electromyography (EMG).
- Electroencephalography (EEG) [Routine and sleep deprived]
- Botulinum toxin for hemifacial spasms, blepharospasms, cervical dystonia, axillary hyperhidrosis, chronic migraines, upper limb spasticity and lower limb spasticity.
- Occipital nerve blocks with lignocaine/steroids.
My goal is to deliver thorough, evidence-based neurological care, supported by advanced neurophysiology to guide accurate diagnosis and treatment
Dr Jayamanne focuses on delivering care that is:
Professional Qualifications
MBBS
BMSc
PhD
FRACP
Associated organisations
ANZAN
Australia New Zealand association of neurologists.
Neuromuscular society Australia
Neuroimmunology Australia
Conjoint associate lecture at University of Notre Dame, School of medicine.
Professional profiles
Research interest/publications:
- Actions of the FAAH inhibitor URB597 in chronic pain states. Angelo Jayamanne1, Ruth Greenwood1, Vanessa Mitchell1, Sevda Aslan1, Danielle Piomelli2 & Christopher Vaughan1. 1Pain management Research Institute, University of Sydney, Sydney, Australia. 2Department of pharmacology, University of California, Irvine, USA. British journal of Pharmacology (1-8) December 2005.
- muO-conotoxin MrVIB selectively blocks Nav1.8 sensory neuron specific sodium channels and chronic pain behavior without motor deficits. Ekberg J, Jayamanne A, Vaughan CW, Aslan S, Thomas L, Mould J, Drinkwater R, Baker MD, Abrahamsen 5 B, Wood JN, Adams DJ, Christie MJ, Lewis RJ. Proceedings of the National Academy of Sciences, U.S.A. 2006 Nov 7;103(45):17030-5.
- Actions of the endocannabinoid transport inhibitor AM404 in neuropathic and inflammatory pain models. Vanessa Mitchell, Ruth Greenwood, Angelo Jayamanne, Christopher Vaughan. Clinical and experimental pharmacology and physiology. (2007), 34, 1186-1190.
- Spinal actions of ω-conotoxins, CVID, MVIIA and related peptides in a rat neuropathic pain model. Jayamanne A, Jeong HJ, Schroeder CI, Lewis RJ, Christie MJ, Vaughan CW. Br J Pharmacol. 2013 Sep; 170(2):245-54.
- Gamma-aminobutyric acid-B limbic encephalitis and asystolic cardiac arrest: a case report. Ovens CA, Jayamanne A, Duggins. A Journal of medical case reports. 2017 Dec 29; 11(1): 361.
Locations & Availability
Complete Health Australia Rouse Hill

Why Choose CHA?
Every patient receives a thorough assessment and an individualised care plan.